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Combination therapies Combination therapies that integrate microbiome-targeted interventions with traditional antidepressants or weight loss medications represent a promising frontier in treating both obesity and depression

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In patients with elevated concentration of chylomicron triglycerides and VLDL triglycerides (polygenic chylomicronaemia), diet is very important, although more difficult to implement, as it should be targeted at reduction of chylomicron synthesis in the intestinal epithelium, so fat intake must be very limited ( 2.3 mmol/l (200 mg/dl), treatment is always initiated with a statin (atorvastatin or rosuvastatin)

This activation enhanced host antioxidant capacity and mitigated postpartum oxidative stress 86,87