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The absence of STAT5 results in higher levels of lipogenesis and lipid accumulation in the liver, along with increased activation of tumor-promoting pathways such as STAT3 and c-Jun

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Several mechanisms have been proposed for NAC- or HPN-07-induced neurogenesis, potentially involving activation of the Ras-ERK cascade and the PKC pathway 30,31,32

Plateaus can be reached way before significant weight loss is achieved, especially with severely or morbidly obese patients who use these medications as first line treatment