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14,23 The American Academy of Dermatology 2024 treatment guidelines state that topical therapies such as retinoids serve as the cornerstone of acne treatment since they enable maintenance of acne clearance. 2 A systematic review from 2016 included six maintenance studies of the topical retinoids adapalene 0.1% gel and tazarotene 0.1% gel alone or in combination with other treatments

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