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SKU: 98048671918

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Notch1 inhibition alters the CD44hi/CD24lo population and reduces the formation of brain metastases from breast cancer

05.3 Dati preclinici di sicurezza Prove di tossicit acuta effettuate sul ratto e sul Mus musculus per 7 giorni consecutivi hanno permesso di stabilire per la DL50 un dosaggio superiore a 8000 mg/kg per la via orale e a 4000 mg/kg per l'iniettiva