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Ann Emerg Med 17(7):728731 Guay J, Grenier Y, Varin F (1998) Clinical pharmacokinetics of neuromuscular relaxants in pregnancy

Despite wide dose ranges tested (6 g/kg to 20 mg/kg), multiple administration routes (intramuscular, intraperitoneal, intravenous, oral), and varied dosing frequencies across numerous animal models, no acute lethal dose has been identified

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This would be expected to have an effect on the rates amino-acid-requiring processes of one-carbon metabolism and glutathione synthesis