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If your weight loss stalls after initial progress, the solution usually involves one or more of these adjustments: increasing your dose (if medically appropriate), tightening nutrition, adding or increasing exercise, managing stress and sleep, or splitting your dose

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Dual agonism: Tirzepatide borrows the first ten amino acids from exendin-4 and the rest from human GIP, creating a synergistic effect on both GIP and GLP-1 receptors

Zhang W, Waise TMZ, Toshinai K, et al