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Burman, P., Ritzn, E

They can be taken together without negative interactions, though starting with one at a time allows you to assess individual responses

Anti-doping regulations consider them a form of doping that provides an unfair advantage

Coffee enemas are known to cause the following problems: Cramps Nausea Diarrhea Rectal Burns Rectal Puncture Vomiting Bloating Bowel Perforation Dehydration Long-term risks from frequent use of coffee enemas include: Colitis an inflammation of the lining of the colon Proctocolitis an inflammation of the rectum Severe dehydration and electrolyte imbalance Septicemia also called sepsis (blood poisoning) The National Cancer Institute reports three known deaths from coffee enemas: two from electrolyte imbalances and one from septicemia (blood poisoning)