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While our nested casecontrol design, PSM analyses, dynamic PDC-based exposure assessment, and subgroup analyses help mitigate these concerns, they cannot fully eliminate them

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None of these peptides are FDA-approved drugs

In the case that you are overmethylating, yet are still deficient in folate and B12, you may want to avoid methylated versions of folate (methylfolate) and B12 (methylcobalamin), and consider non-methylated but active versions of folate (folinic acid) and B12 (adenosylcobalamin and/or hydroxocobalamin)