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The resulting 1st generation GLP-1 agonists were introduced with the approval of Amylins Byetta (exenatide) in 2005 and Novos Victoza (liraglutide) in 2010 in adults with type 2 diabetes

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The highest antibody (IgG) serum levels were seen in the following distribution of subjects studied: (8) Mean values for half-life were between 17.5 and 25 days, with the shortest being 5.9 days and the longest 35 days.(8) Cases of type B hepatitis are rarely seen following exposure to HBV in persons with preexisting anti-HBs