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Gclc deficiency in mouse CNS causes mitochondrial damage and neurodegeneration

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According to research findings, approximately 40 microRNAs have been observed to impact redox signaling, potentially in the onset of CVD or as a protective measure against it (205)

Alterations in mitochondrial dynamics lead to a range of metabolic abnormalities: impaired oxidative phosphorylation, defective mitochondrial gene expression, imbalances in fuel and energy homeostasis, increased ROS production, enhanced insulin resistance, and abnormal FA metabolism