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The distinctiveness of the microvasculature of the CNS in the presence of non-fenestrated vessels as well as other additional components help in strictly controlling the influx and efflux of various molecules, ions, and other important cells across the blood and brain barrier [6]

Ethical and Regulatory Challenges: Regulatory approval for senolytic drugs is challenging because aging is not officially classified as a disease by the Food and Drug Agency (FDA) or European Medicine Agency EMA, making it harder to obtain approval for anti-aging treatments

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