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In research protocols, this can be either desirable (for models examining appetite regulation, weight gain, or catabolic disease states) or undesirable (for protocols where appetite stimulation is a confounder)

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Furthermore, CLA supplementation (78% total CLA, with 37% of the oil as c9, t11 isomers and 37% as t10, c12 isomers) for 6 weeks at a dose of 5.6 g/day had no effect on physical performance in young athletes, as assessed by VO2 max, physical working capacity, and gas exchange threshold [99]

A meta-nalysis showed that, compared with placebo/no intervention, the treatment with acetyl-l-carnitine significantly decreased the symptoms of depression, with fewer adverse events than those seen with established antidepressants [94]