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The strains, the mechanisms, the clinical data, the limitations, and the practical details that most reviews skip entirely
In addition, TR-12@LGMN immunization elicited strong tumor-specific immune responses, such as infiltration of effecter memory T cells and antigen-specific CTLs, offering lasting tumor immunity as well as synergizing with PD-1 blockade in enhanced therapeutic efficacy
2.6 Mitochondrial impairment causes reduction of enteroendocrine cells Intriguingly, deletion of the mitochondrial chaperone Hsp60 in murine colonocytes, triggering mitochondrial dysfunction and stress signaling, resembles the metabolic fingerprint of inflammation including up-regulation of Hk2 and Ddit4 , as well as down-regulation of Pck1 and Hmgcs2 (65)
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