is farxiga a glp-1 Glucagon-like peptide-1 receptor: mechanisms and advances in therapy T2DM Therapeutic Area Landscape: SGLT2

Early small trials of liraglutide ( n = 38) and exenatide ( n = 18) reported no significant cognitive or biomarker effects, although exploratory analyses indicated preserved cerebral glucose metabolism (74) and reduced NDEV A42 (62)

At high concentrations, these substances have toxic effects on bone cells, potentially leading to increased apoptosis and decreased bone formation (13)

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