For the once-weekly subcutaneous formulation, the SUSTAIN program (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) included 13 separate randomized clinical phase 3a and 3b trials ( Table 1 Overview of Phase 3 studies of oral semaglutide (PIONEER) and subcutaneous semaglutide (SUSTAIN) ( *Phase 3b trials all others are phase 3a trials CKD, chronic kidney disease
Scientists and researchers are currently doing studies to further understand the differences
Wegovy Dry Mouth: How to Manage Dry Mouth from Semaglutide HOME | DIABETES EDUCATION | WEGOVY DRY MOUTH: HOW TO MANAGE DRY MOUTH FROM SEMAGLUTIDE Dry mouth (xerostomia) is a known Wegovy side effect affecting up to 10% of users
J Med Chem 58:73707380 Lee TS, Park EJ, Choi M, Oh HS, An Y, Kim T, Kim TH, Shin BS, Shin S (2023) Novel LC-MS/MS analysis of the GLP-1 analog semaglutide with its application to pharmacokinetics and brain distribution studies in rats