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Quercetin synergistically potentiates the anti-metastatic effect of 5-fluorouracil on the MDA-MB-231 breast cancer cell line

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In the study of endometrial cancer (EC), we found that Brusatol sensitizes the cancer to progestins by inhibiting the NRF2-TET1-AKR1C1 pathway, which reduces AKR1C1 expression and decreases progesterone metabolism [110]

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Recent clinical trials show 20mg daily (the exact dose used in the Longevity Multi) produces significant improvements in cognitive function, including enhanced processing speed and memory performance

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