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Pernicious anaemia is caused by a deficiency in vitamin B12, due to atrophic gastritis, an autoimmune condition (immune system destroys self), in this case the parietal cells of the stomach that produce intrinsic factor, a glycoprotein that binds to vitamin B12 in the stomach and is essential for normal absorption of vitamin B12 in the small intestine into the blood

Folic acid (vitamin B9) works synergistically with B12, helping in the production of red blood cells and supporting healthy nerve function

Vitamin B12 deficiency can cause symptoms such as fatigue, weakness, numbness or tingling in the hands and feet, balance problems, and memory difficulties

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