To perform Na + dependence assays, carnitine doses were applied to oocytes expressing hOCTN2, and related mutants, in the presence of Cl - buffers of differing Na + concentration (10100 mM NaCl, 100 mM - [NaCl] CsCl, 2 mM KCl, 1 mM MgCl 2 , 1.8 mM CaCl 2 , 5 mM HEPES, buffered to pH 7.4 with Tris base)
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Moreover, the number of CD8 + T cell infiltrates was positively correlated with the serum creatinine level, proteinuria, the ratio of glomerulosclerosis and the degree of tubulointerstitial inflammation, interstitial fibrosis and tubular atrophy in patients with lupus nephritis [132]