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Clinical research has demonstrated that elevated lipid peroxidation is associated with a higher risk of treatment-resistant depression, while antidepressants like fluoxetine and citalopram have been found to reduce MDA levels in MDD patients

Somasundaram S, Rafi S, Hayllar J et al (1997) Mitochondrial damage: a possible mechanism of the topical phase of NSAID induced injury to the rat intestine