glutathione peroxidase sigma Superoxide dismutase (SOD), (GPx), glutathione ensuring smooth and accurate processing glutathione reductase sigma peroxidase glutathione

Regulation of GSK3/Nrf2 signaling pathway modulated erastin-induced ferroptosis in breast cancer

Genome-wide association studies of posttraumatic stress disorder in 2 cohorts of US army soldiers

Stops mutations Stops molecules inert, preventing their destructive effects Vital for both phase I & phase II liver detoxification Induces normal p53(tumor suppressor) activity by redox modulation, which induces apoptosis in tumor cells Detoxification is another major function

We first examine intrinsic mechanismsincluding drugtarget alterations, dysregulated drug metabolism and efflux, hyperactivation of DNA damage repair pathways, and epigenetic remodelingand extrinsic influences stemming from the tumor microenvironment and extracellular matrix remodeling