However, despite encouraging preclinical results, clinical translation remains limited and will likely require combined strategies that address both upstream immune dysregulation (to induce tolerance) and ongoing symptoms
For example, 1 g of taurine administration improved the 3-km time trail running before the exercise, whereas during the 4-km running trail did not have a significant effect on exercise performance with taurine supplementation ( The effect of the duration of taurine administration in increasing exercise performance is ambiguous
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In light of these findings, we postulated that long-term fluctuating glycemia, especially after extra carbohydrate intake, continuously and waveringly generates extra ROS, which in turn damages the pancreatic -cells
